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  • Title: Isolation and characterization of fusaproliferin, a new toxic metabolite from Fusarium proliferatum.
    Author: Ritieni A, Fogliano V, Randazzo G, Scarallo A, Logrieco A, Moretti A, Mannina L, Bottalico A.
    Journal: Nat Toxins; 1995; 3(1):17-20. PubMed ID: 7749578.
    Abstract:
    A new toxic sesterterpene, named fusaproliferin, was purified from corn kernel cultures (120 mg/kg dry culture) of a strain of Fusarium proliferatum isolated from corn ear rot in northern Italy. The stain, designated ITEM-1494, also produced fumonisin B1 (1.500 mg/kg dry culture) and beauvericin (90 mg/kg dry culture), but not moniliformin. To monitor toxicity, the brine shrimp assay was used throughout the isolation procedure. Fusaproliferin had a molecular formula of C27H40O5, and it is the first sesterterpene isolated from a Fusarium species.
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