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  • Title: ATP opens an electrophoretic potassium transport pathway in respiring yeast mitochondria.
    Author: Roucou X, Manon S, Guerin M.
    Journal: FEBS Lett; 1995 May 08; 364(2):161-4. PubMed ID: 7750562.
    Abstract:
    In the presence of KCl and only at low phosphate concentrations, ATP stimulated state 4 of the respiration of isolated yeast mitochondria. This effect could be related to a partial collapse of the transmembrane potential which was created by the respiratory chain or the F0F1-ATPase. Sodium and lithium could not replace potassium ion. Atractyloside prevented the opening of this K+ pathway, suggesting that only matricial ATP operated. All these effects were inhibited by increasing phosphate concentration, or by adding propranolol, quinine, Zn2+ or Mg2+.
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