These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Dieting decreases plasma tryptophan and increases the prolactin response to d-fenfluramine in women but not men.
    Author: Walsh AE, Oldman AD, Franklin M, Fairburn CG, Cowen PJ.
    Journal: J Affect Disord; 1995 Feb 21; 33(2):89-97. PubMed ID: 7759666.
    Abstract:
    We studied the effect of 3 weeks of moderate calorie restriction on 5-HT-mediated prolactin (PRL) release in healthy volunteers using the 5-HT-releasing agent d-fenfluramine. In women, dieting significantly lowered plasma total and free tryptophan (TRP) and increased the PRL response to d-fenfluramine. None of these measures were altered in men who dieted. These findings add to the data indicating that dieting alters brain 5-HT function in women, perhaps as a consequence of reducing the availability of plasma TRP.
    [Abstract] [Full Text] [Related] [New Search]