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Title: [Study of the effect of rifampicin on certain immunological and protective reactions of the body]. Author: Shapovalova SP, Malkova IV. Journal: Antibiotiki; 1976 Feb; 21(2):159-62. PubMed ID: 776073. Abstract: The effect of rifampicin on formation of hemagglutinins in mice in response to administration of sheep erythrocytes was studied. The experiments showed that rifampicin administered orally in doses 10-25 times higher than the therapeutic ones did not suppress formation of the antibodies and protective mechanisms of the organism. The antibiotic did not lower the absorbing capacity of the cells by the reticuloendothelial system and the rate of phagocytosis by the leucocytes of the peritoneal exudate in mice. Rifampicin had no effect as well on adaptation of a skin homotransplant in the animals.[Abstract] [Full Text] [Related] [New Search]