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  • Title: [Immunoscintigraphy of bone marrow in plasmacytoma].
    Author: Bathmann J, Brugger W, Ullrich C, Mertelsmann R, Moser E.
    Journal: Nuklearmedizin; 1995 Apr; 34(2):66-70. PubMed ID: 7761276.
    Abstract:
    In 26 patients with plasmocytoma and 4 patients with benign monoclonal gammopathy bone marrow scintigraphy using 99mTc-labelled monoclonal antigranulocyte-antibodies was performed. Focal marrow defects were found in 18/26 patients with plasmocytoma but in none with benign monoclonal gammopathy. The results in plasmocytoma patients correlated well with the clinical staging system of Durie and Salmon. Quantification showed a suppressed bone marrow uptake ratio in 8/26 patients. A marked bone marrow expansion was present in only 2/26 patients. Bone marrow scintigraphy seems to be a valuable diagnostic tool in patients with plasmocytoma, especially as it is able to visualize the degree of bone marrow infiltration in a single protocol and so allows to follow up patients in a simple noninvasive manner.
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