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  • Title: Silicone elastomer microshards in fluid from a painful metatarsophalangeal implant site. A case report.
    Author: Friedlander GN, Potter GK, Tucker RS, Berlin SJ.
    Journal: Acta Cytol; 1995; 39(3):586-8. PubMed ID: 7762357.
    Abstract:
    Histopathologic studies have demonstrated microshards from silicone elastomer metatarsophalangeal joint implants in adjacent tissues in a setting of chronic inflammation and in inguinal lymph nodes. Cytologic smears of synovial fluid from symptomatic implanted joints should show these refractile, nonpolarizing microshards in the reactive inflammatory context. Nonspecific enzymatic inflammatory activity contributes to further destabilization of the implants, eventuating in symptoms and signs requiring prosthesis removal. Cytopathologic examination of aspirated fluid from the vicinity of a symptomatic implanted joint demonstrates foreign body reaction to silicone elastomer, predicting a need for intervention before the local damage is severe and disabling.
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