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  • Title: Diazepinoquinazolines. Part II. Synthesis and pharmacological activity of some derivatives of 1,4-diazepino[2,1-b]quinazoline.
    Author: Guryn R, Szadowska A, Pakulska W.
    Journal: Acta Pol Pharm; 1994; 51(6):483-7. PubMed ID: 7762399.
    Abstract:
    New derivatives of 1,4-diazepino[2,1-b]quinazoline were obtained. The diazepino quinazoline [IV] was obtained by the condensation of 2,5,6,7-tetrahydro-3-(methylthio)-1-phenyl-1H-1,4-diazepine with 5-chloroantranilic acid. Compounds was preparated in two steps from 2,3,4,5-tetrahydro-1,4-diazepino[2,1-b]quinazolin-7(1H)-one. The derivatives [II-IV], [VII], [VIII] were screened for their psychotropic activity.
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