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Title: Synthesis and activity of dipeptides containing epsilon-aminocaproic acid. Author: Midura-Nowaczek K, Bruzgo I, Roszkowska-Jakimiec W, Worowski K. Journal: Acta Pol Pharm; 1994; 51(6):499-504. PubMed ID: 7762400. Abstract: Five new dipeptides containing epsilon-aminocaproic acid were synthesized. All dipeptides markedly inhibit fibrinolytic activity of plasmin but only in low concentration (0.0002M). In higher concentration fibrinolytic activity was observed. Activity of dipeptides containing epsilon-aminocaproic acid, which antifibrinolytic activity is known, was tested on plasmin, thrombin, urokinase and euglobulin fraction using synthetic substrates.[Abstract] [Full Text] [Related] [New Search]