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  • Title: His273 of 3-isopropylmalate dehydrogenase from Thermus thermophilus HB8 is involved in the coenzyme binding.
    Author: Yaoi T, Miyazaki K, Oshima T.
    Journal: Biochem Biophys Res Commun; 1995 May 25; 210(3):733-7. PubMed ID: 7763246.
    Abstract:
    The coenzyme binding site of NAD(+)-dependent 3-isopropylmalate dehydrogenase from Thermus thermophilus was analyzed by chemical modification and site-directed mutagenesis, and His273 of the enzyme was identified to be involved in the coenzyme binding.
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