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  • Title: 15-hydroperoxydehydroabietic acid--a contact allergen in colophony from pinus species.
    Author: Shao LP, Gäfvert E, Nilsson U, Karlberg AT, Nilsson JL.
    Journal: Phytochemistry; 1995 Mar; 38(4):853-7. PubMed ID: 7766387.
    Abstract:
    A new hydroperoxide, 15-hydroperoxydehydroabietic acid (15-HPDA), with contact allergenic properties has been detected in rosin obtained from Pinus species. Detection was facilitated using a synthetic preparation of 15-HPDA for reference purposes. The synthesis and the detection (HPLC and GC) of 15-HPDA in rosin are described. The allergenic activity of 15-HPDA was studied in an experimental sensitization test on guinea-pigs.
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