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  • Title: Cardiac complication from use of cocaine and phenylephrine in nasal septoplasty.
    Author: Ashchi M, Wiedemann HP, James KB.
    Journal: Arch Otolaryngol Head Neck Surg; 1995 Jun; 121(6):681-4. PubMed ID: 7772323.
    Abstract:
    Cocaine hydrochloride is widely used as a topical anesthetic for otolaryngologic surgery. Cardiovascular complications, including myocardial injury, are well-documented side effects of illicit cocaine use. We describe a 23-year-old woman without coronary artery disease who had an acute non-Q-wave myocardial infarction and stunned myocardium after receiving topical phenylephrine hydrochloride and cocaine anesthesia for elective nasal septoplasty. These cases are rare; however, we hope to heighten the awareness of the potential lethal complications of using cocaine, phenylephrine, or the combination of both as topical anesthetics in otolaryngologic practice.
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