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  • Title: Monoclonal antibody studies on rabies-related viruses.
    Author: King AA.
    Journal: Onderstepoort J Vet Res; 1993 Dec; 60(4):283-7. PubMed ID: 7777312.
    Abstract:
    Rabies and rabies-related viruses are divided into four serotypes, although it has been suggested that the inclusion of European bat lyssaviruses results in six genotypes. Sixty-four rabies-related viruses were tested against a panel of 36 anti-nucleocapsid monoclonal antibodies prepared from the immunization of Balb/c mice with five prototypic rabies-related viruses. Reaction patterns obtained confirmed the original distinction between serotype 1-4 viruses and revealed multiple variants of Lagos bat and Mokola viruses. In addition, two biotypes of European bat lyssavirus were identified and a clear distinction was shown between these biotypes and Duvenhage virus of Africa. The origins and importance of the rabies-related viruses are discussed.
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