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  • Title: [Effectiveness of isoniazid in tuberculosis chemoprophylaxis in children with rising tuberculin sensitivity].
    Author: Mitinskaia LA, Elufimova VF, Iukhimenko NV, Demeshko ND, Zriachkina LI, Pesnia NP.
    Journal: Probl Tuberk; 1995; (2):5-6. PubMed ID: 7777467.
    Abstract:
    70 children aged 4-15 with growing tuberculin sensitivity received preventive treatment with isoniazid in children's sanatorium. The drug was taken for 2 or 3 months in a dose 10 mg/kg daily (19 and 51 children, respectively). Preventive isoniazid course proved effective as none of the children treated developed tuberculosis within 3 years. The 3-month course is preferable as it is more potent in relation to tuberculin sensitivity immediately after the treatment termination and 1, 2 years after it.
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