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  • Title: [Application of T-subgroup cells assay in the immunology of oral-maxillofacial cancer].
    Author: Lu C, Yin D, Cao D.
    Journal: Zhonghua Kou Qiang Yi Xue Za Zhi; 1995 Jan; 30(1):29-31, 64. PubMed ID: 7789230.
    Abstract:
    We report on T-subgroup cells in 70 cases of oral-maxillofacial cancer determined by T-monoclone antibody-OKT system. The results are as follows: CD3, CD4/CD8 value of cancer patients was decreased significantly, compared with that of health or oral benign tumor patients. CD8 was significantly increased (P < 0.001); however, CD8 was decreased and CD4/CD8 ratio was increased after operation. 20 cases underwent the dynamic testing, determined in 1 week, 1 and 3 month. The results are as follows: CD3, CD4, CD4/CD8 values were increased gradually and CD8 was decreased gradually in 17 cases of curative patients, but CD4, CD4/CD8, values were decreased and CD8 was increased significantly in 3 cases of metastased patients. Our conclusion is that determination of T-subgroup cells is of reference value for monitoring and treating cancer patients.
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