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  • Title: [Neoadjuvant chemotherapy of liver tumors metastasized by sigmoid colon cancer: a case report of CDDP/5-FU intraarterial infusion therapy followed by hepatectomy].
    Author: Yamashita F, Tanaka M, Yutani S, Shimada M, Kusaba T, Kuroki S, Inoue J, Katoh O, Sasatomi K, Tanikawa K.
    Journal: Gan To Kagaku Ryoho; 1995 Jun; 22(7):949-52. PubMed ID: 7794002.
    Abstract:
    A case of liver tumors metastasized by Sigmoid colon cancer was treated with intrahepatic arterial infusion of CDDP (10 mg) and 5-FU (250 mg) via subcutaneously implanted reservoir. After 20 administrations of CDDP and 5-FU, the tumors in the right lobe of the liver disappeared, but those in the left lobe remained. Therefore left hepatectomy was carried out. Six months after the hepatectomy, a nodule recurrence was disclosed in the right lobe of the liver. With re-elevated serum CEA level, subsequent intrahepatic arterial infusion of CDDP and 5-FU the nodule size reduced with normalization of the serum CEA level.
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