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  • Title: Metachronous small-bowel adenocarcinoma in celiac sprue.
    Author: Begos DG, Kuan S, Dobbins J, Ravikumar TS.
    Journal: J Clin Gastroenterol; 1995 Apr; 20(3):233-6. PubMed ID: 7797833.
    Abstract:
    Celiac sprue, or nontropical sprue, is associated with an increased incidence of digestive tract malignancy. We report a patient with celiac sprue who developed two primary adenocarcinomas of the jejunum > 2 years apart. The second cancer was asymptomatic and detected by surveillance computed tomography. Small-bowel cancers are unusual, and frequency of follow-up has not been established, so that it is important to have a high index of suspicion for these malignancies in celiac patients with vague gastrointestinal symptoms.
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