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  • Title: Goodpasture's syndrome in childhood: treatment with plasmapheresis and immunosuppression.
    Author: McCarthy LJ, Cotton J, Danielson C, Graves V, Bergstein J.
    Journal: J Clin Apher; 1994; 9(2):116-9. PubMed ID: 7798157.
    Abstract:
    Goodpasture's syndrome rarely affects children. Therefore, we present our experience in a young boy whose pulmonary hemorrhage was dramatically resolved by three plasma exchanges. We believe the hemorrhage was caused primarily by acute capillaritis. He received cytoxan and steroids and a series of plasma exchanges which removed/suppressed his anti-glomerular basement membrane (anti-GBM) antibody production. However, after a year, his renal function did not return, and he required renal transplantation and continues to do well.
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