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  • Title: Hypouricemia, hypokalemia, proximal and distal tubular acidification defect following administration of outdated tetracycline: a case report.
    Author: Chusil S, Tungsanga K, Wathanavaha A, Pansin P.
    Journal: J Med Assoc Thai; 1994 Feb; 77(2):98-102. PubMed ID: 7798843.
    Abstract:
    A Thai female patient developed muscular weakness, hypouricemia, hypokalemia and hyperchloremic metabolic acidosis after taking outdated tetracycline. A pathophysiologic study shows a proximal tubular defect for reabsorption of urate and bicarbonate and a distal tubular acidification defect, probably caused by outdated tetracycline.
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