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  • Title: PET versus SPECT in distinguishing radiation necrosis from tumor recurrence in the brain.
    Author: Buchpiguel CA, Alavi JB, Alavi A, Kenyon LC.
    Journal: J Nucl Med; 1995 Jan; 36(1):159-64. PubMed ID: 7799071.
    Abstract:
    Two cases of postsurgical brain tumor evaluation in which MRI was inconclusive are discussed. Functional imaging techniques, such as FDG-PET and 201TI SPECT, were used in both cases for distinguishing radiation necrosis from tumor recurrence. These methods proved to be complimentary. For Patient 1, FDG-PET showed more limitations compared to 201TI SPECT. FDG-PET results on the other hand, were consistent with the final diagnosis and the SPECT image was false positive for tumor recurrence in Patient 2.
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