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  • Title: A new antibiotic, cypemycin. Taxonomy, fermentation, isolation and biological characteristics.
    Author: Komiyama K, Otoguro K, Segawa T, Shiomi K, Yang H, Takahashi Y, Hayashi M, Otani T, Omura S.
    Journal: J Antibiot (Tokyo); 1993 Nov; 46(11):1666-71. PubMed ID: 7802859.
    Abstract:
    A new peptide antibiotic, cypemycin, with a molecular weight of 2,097 (M+H), was isolated from the culture broth of Streptomyces sp. OH-4156. The antibiotic possesses cytocidal activity against P388 leukemia cells in vitro at a concentration of 1.3 microgram/ml (IC50 values), and the antibiotic showed antimicrobial activities against Micrococcus luteus (MIC, 0.2 microgram/ml).
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