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Title: Excretion of 3-hydroxy-diflunisal as a monosulphate conjugate--identification using ESI-MS. Author: Dickinson RG, King AR, Kelly MA, Kaltashov IA, Fenselau C. Journal: J Pharm Biomed Anal; 1994 Sep; 12(9):1075-8. PubMed ID: 7803554. Abstract: Electrospray-ionization mass spectrometry was used to identify a novel, highly polar metabolite of diflunisal isolated from Gunn rat urine. Negative ion spectra were obtained of the sulphate conjugate of diflunisal and the new metabolite, which was identified as a sulphate conjugate of 3-hydroxydiflunisal.[Abstract] [Full Text] [Related] [New Search]