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  • Title: Matching for HLA antigens of A, B, and DR loci in renal transplantation by Eurotransplant.
    Author: Persijn GG, Gabb BW, van Leeuwen A, Nagtegaal A, Hoogeboom J, van Rood JJ.
    Journal: Lancet; 1978 Jun 17; 1(8077):1278-81. PubMed ID: 78047.
    Abstract:
    79 patients and their respective cadaveric kidney donors were typed for HLA-A, HLA-B, and HLA-DR antigens using frozen stored spleen lymphocytes and fresh peripheral-blood lymphocytes. The kidney-graft survival-rate at 3 to 18 months was highest when donor and recipient shared one or two DR antigens and three or four A and B antigens. The graft-survival rate was significantly higher (87 +/- 6%) at 18 months in these patients than in less well matched patients (48 +/- 9%).
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