These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Antimalarials. 9. Methylthio- and methylsulfonyl-substituted 9-phenanthrenemethanols.
    Author: Markovac A, LaMontagne MP.
    Journal: J Med Chem; 1976 Jul; 19(7):978-82. PubMed ID: 781249.
    Abstract:
    Nine di- and trisubstituted 9-phenanthrenemethanols bearing methylthio and methylfulfonyl substituents in the 2 and/or 6 positions of the phenanthrene nucleus were prepared and screened for antimalarial activity against Plasmodium berghei in mice. Six of the nine compounds were curative at or below 160 mg/kg. The most active structures contained a methylthio substituent in combination with two chlorine atoms.
    [Abstract] [Full Text] [Related] [New Search]