These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Immunolocalization of mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase in rat liver.
    Author: Royo T, Pedragosa MJ, Ayté J, Gil-Gómez G, Vilaró S, Hegardt FG.
    Journal: J Cell Physiol; 1995 Jan; 162(1):103-9. PubMed ID: 7814442.
    Abstract:
    We report the preparation of specific polyclonal antibodies raised against two synthetic peptides deduced from the cDNA sequence for the rat liver mitochondrial 3-hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) synthase gene. Immunoelectron microscopy using these antibodies on hepatic cryoultrathin sections confirms the mitochondrial localization of this protein in hepatocytes. Immunofluorescence microscopy on frozen sections of adult rat liver revealed fluorescence inside all hepatocytes, with no evidence of zonation, indicating that ketogenesis may not be limited to specific regions of rat liver but is extended to all hepatocytes.
    [Abstract] [Full Text] [Related] [New Search]