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  • Title: Protection against homologous but not heterologous challenge induced by inactivated feline immunodeficiency virus vaccines.
    Author: Hosie MJ, Osborne R, Yamamoto JK, Neil JC, Jarrett O.
    Journal: J Virol; 1995 Feb; 69(2):1253-5. PubMed ID: 7815500.
    Abstract:
    Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8) which is distinct from the Petaluma strain in virus neutralization. Protection was associated with a type-specific neutralizing antibody response and was retained when the challenge virus was propagated in an unrelated cell line.
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