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  • Title: [Pulmonary capacity and volume, forced expiratory flow measured by whole body plethysmography in acute pancreatitis: experimental study in rats].
    Author: Chaib E, Saldiva PH, Criado PM, Sakae RS, Machado MC.
    Journal: Rev Hosp Clin Fac Med Sao Paulo; 1994; 49(2):60-3. PubMed ID: 7817094.
    Abstract:
    Up to 70% of the patients with acute pancreatitis suffer a sort of pulmonary dysfunction. Twenty-nine rats with pancreatitis induced by 2.5% taurocholic and solution have been studied by whole body plethysmography in order to evaluate pulmonary volumes and expiratory flows. They were divided into three groups: a sham operation control group-10 rats,a two pancreatitis group-10 rats and eight hours pancreatitis group-9 rats. The results showed a significant decrease of expiratory reserve volumes and forced vital capacity (FVC) and also a significant increase of expiratory flow in the 2 and 8 hours pancreatitis groups. These findings indicate a restrictive pneumopathy.
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