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  • Title: Immunohistochemical localization of the neuron-specific glucose transporter (GLUT3) to neuropil in adult rat brain.
    Author: McCall AL, Van Bueren AM, Moholt-Siebert M, Cherry NJ, Woodward WR.
    Journal: Brain Res; 1994 Oct 03; 659(1-2):292-7. PubMed ID: 7820678.
    Abstract:
    The precise histologic localization of GLUT3, a glucose transporter thought to be restricted to neurons, is unknown. Using a high-affinity, specific antiserum against rodent GLUT3 for immunocytochemistry, light microscopic staining concentrates heterogeneously in the neuropil in a region- and lamina-specific manner; intense staining characterizes areas with high rates of glucose utilization such as inferior colliculus and pyriform cortex. Neuropil localization with little perikaryal staining suggests that GLUT3 may provide the energy needed locally for synaptic transmission.
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