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  • Title: Intramuscular butorphanol and meperidine in postoperative pain.
    Author: Gilbert MS, Hanover RM, Moylan DS, Caruso FS.
    Journal: Clin Pharmacol Ther; 1976 Sep; 20(3):359-64. PubMed ID: 782774.
    Abstract:
    Butorphanol, 1, 2, and 4 mg/70 kg, and meperidine, 40 and 80 mg/70 kg, were compared for analgesic activity and side effects in 104 hospitalized postoperative patients. Butorphanol proved to be 30 to 40 times as potent as meperidine on a weight basis. Both medications provided maximum pain relief approximately 1 hr after administration. The most common side effect in all groups was drowsiness.
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