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  • Title: Immunohistochemical staining for thyroglobulin in poorly differentiated carcinoma of the thyroid.
    Author: Ratnatnga N, Ramadasa S.
    Journal: Ceylon Med J; 1993 Sep; 38(3):113-6. PubMed ID: 7828228.
    Abstract:
    Paraffin sections of 14 specimens of poorly differentiated tumours of the thyroid were stained for thyroglobulin using polyclonal antibodies and a streptavidin-biotin peroxidase staining system. The better differentiated areas showed positive staining, while the poorly differentiated areas gave weakly positive or negative staining. Thyroglobulin staining is useful in attributing a thyroid epithelial cell origin to a tumour, but negative staining does not exclude this.
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