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  • Title: Cutaneous manifestations of renal transplantation in a New Zealand population.
    Author: Hepburn DJ, Divakar D, Bailey RR, Macdonald KJ.
    Journal: N Z Med J; 1994 Dec 14; 107(991):497-9. PubMed ID: 7830977.
    Abstract:
    AIM: To document the skin manifestations of renal transplant recipients. METHODS: The findings in 52 patients (27 males; mean age 43.5 yr; range 22-74 yr; SD 12.0) with a stable renal transplant for a mean of 115.6 mth (range 3-258; SD 70.6). Thirty seven patients were on prednisone and azathioprine and 18 on prednisone, azathioprine and cyclosporin. RESULTS: Including prior observations, 48 cutaneous malignancies were identified in nine patients, with the ratio of squamous cell to basal cell carcinoma being 1.2:1. No metastases were detected. Actinic keratoses were present in 20 patients and tended to be multiple and present on sun exposed skin. A wide range of nonneoplastic lesions was documented, including warts in 75%. Human papillomavirus was isolated from 43% of warts. CONCLUSIONS: Renal transplant recipients require regular skin examination. Patients with high recreational or work related sun exposure prior to, or after transplantation, and those who have had a previous skin malignancy, should be identified as high risk patients for skin cancer and have regular dermatological follow up.
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