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  • Title: [The amino acid composition of the blood serum and gastric mucosa in peptic ulcer with involvement of the hepatobiliary system and intestines in patients of different ages (2)].
    Author: Kolomoets MIu.
    Journal: Lik Sprava; 1994; (5-6):35-40. PubMed ID: 7831906.
    Abstract:
    In ulcerative disease of the stomach the pool of free amino acids (AA) in the mucous membrane of the stomach (MMS) was shown to be expanded, their amount being increased with ageing and in the involvement of the hepatobiliary system, this being a result of even more pronounced augmentation of pathological processes and a decrease in the rate of the protein synthesis. This is accompanied by ever increasing inadequacies in the assimilation of essential amino acids (particularly methionine, threonine, phenilalanine), formation of cystein, glycine, many other essential and conventionally non-essential AA, the process of incorporation of many AA (especially those of sulphur-containing) into polypeptide chain being made difficult, this affecting the synthesis of structural and specific proteins and reducing strikingly the protein-synthesizing potential of MMS.
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