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  • Title: [In vitro study of clastogenic properties of nitrites and nitrates].
    Author: Balimandawa M, de Meester C, Léonard A.
    Journal: C R Seances Soc Biol Fil; 1993; 187(6):744-50. PubMed ID: 7834497.
    Abstract:
    In vitro culture of peripheral blood lymphocytes has been used to evaluate the ability of nitrates (NaNO3) and nitrites (NaNO2) to produce chromosome aberrations in mammalian cells. Whereas treatment with NaNO3 did not increase the spontaneous yield of aberrations, exposure to high doses of NaNO2 resulted in an low increase of micronucleated cells and of chromatid gaps.
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