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  • Title: DNA marker D11S384 shows zero recombination with the ataxia-telangiectasia locus in North American families.
    Author: Lench NJ, Athma P, Ottaiano A, Sribney WM, Highsmith E, Swift M.
    Journal: Int J Radiat Biol; 1994 Dec; 66(6 Suppl):S67-9. PubMed ID: 7836855.
    Abstract:
    At the genetic locus D11S384, one probe detects a Taql RFLP and another detects a RFMP. In 52 pedigrees of North American A-T patients, parental haplotypes based on these two bi-allelic systems have a heterozygosity of 0.69 and a PIC of 0.64. No recombinant events between D11S384 and the A-T locus were detected in the 43 pedigrees in which this marker locus was informative.
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