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  • Title: Plasma lecithin cholesterol acyl transferase activity, high density lipoprotein cholesterol and cholesterol ester in cholestasis.
    Author: Agbedana EO, Taylor GO, Olubuyide IO, Ahaneku JE.
    Journal: Afr J Med Med Sci; 1993 Sep; 22(3):41-4. PubMed ID: 7839911.
    Abstract:
    Lecithin cholesterol acyl transferase activity, cholesterol ester and high density lipoprotein cholesterol concentrations were determined in Nigerian subjects suffering from cholestatic jaundice. Plasma lecithin cholesterol acyl transferase activities in all the study groups were similar. High density lipoprotein cholesterol and cholesterol ester were significantly increased in extrahepatic cholestasis while reduced levels were found in intrahepatic cholestasis. Enhanced cholesterol esterification may occur in extrahepatic cholestasis.
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