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  • Title: Enhancement of 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor alpha production by phenethylphthalimide analogs.
    Author: Sasaki K, Shibata Y, Nishimura K, Hashimoto Y, Iwasaki S.
    Journal: Biol Pharm Bull; 1994 Sep; 17(9):1313-5. PubMed ID: 7841962.
    Abstract:
    Effects of phenyl-, benzyl-, phenethyl-, and phenylpropylphthalimides on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced tumor necrosis factor (TNF)-alpha production by human leukemia cell line HL-60 were examined. Among the four phthalimide derivatives, only phenethylphthalimide showed potent enhancing effect on TNF-alpha production.
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