These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effect of selective 5-HT1A agonists and 5-HT2 antagonists on inherited catalepsy in rats.
    Author: Kulikov AV, Kolpakov VG, Maslova GB, Kozintsev I, Popova NK.
    Journal: Psychopharmacology (Berl); 1994 Feb; 114(1):172-4. PubMed ID: 7846200.
    Abstract:
    The effects of the selective 5-HT1A agonists 8-OH-DPAT and flesinoxan and the selective 5-HT2 antagonists ritanserin and ketanserin on immobility time in rats bred for predisposition to catalepsy have been studied. Treatment with 8-OH-DPAT as well as flesinoxan caused a marked dose-dependent decrease in immobility time. Ritanserin and ketanserin did not affect immobility time at any dose tested. It was suggested that 5HT1A rather than 5-HT2 serotonin receptors are involved in the catalepsy and that an hereditary predisposition to catalepsy may be the result of an inherited alteration in 5-HT1A receptors.
    [Abstract] [Full Text] [Related] [New Search]