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  • Title: DNA-carbohydrate interaction. The effects of mono- and disaccharides on the solution structure of calf-thymus DNA.
    Author: Tajmir-Riahi HA, Naoui M, Diamantoglou S.
    Journal: J Biomol Struct Dyn; 1994 Aug; 12(1):217-34. PubMed ID: 7848569.
    Abstract:
    We report the interaction of calf-thymus DNA with D-glucose, D-fructose, D-galactose and sucrose in aqueous solution at physiological pH with sugar/DNA(P)(P = phosphate) molar ratios (r) of 1/10, 1/5, 1, 5 and 10. FTIR difference spectroscopy was used to characterize the nature of sugar-DNA interaction and correlations between spectral changes and structural variations for both sugar and DNA complexes have been established.
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