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  • Title: Microbial multidrug-resistance ABC transporters.
    Author: Ouellette M, Légaré D, Papadopoulou B.
    Journal: Trends Microbiol; 1994 Oct; 2(10):407-11. PubMed ID: 7850210.
    Abstract:
    Multidrug resistance in tumor cells is often caused by the increased efflux of a wide variety of drugs, mediated by P glycoprotein, a member of the superfamily of ATP-binding cassette (ABC) transporters. The genes encoding members of this superfamily have also been isolated from drug-resistant microorganisms, and the role of microbial ABC transporters in drug resistance is being investigated.
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