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  • Title: An echocardiographic and electrocardiographic study of cardiovascular function in hypothyroid dogs.
    Author: Panciera DL.
    Journal: J Am Vet Med Assoc; 1994 Oct 01; 205(7):996-1000. PubMed ID: 7852177.
    Abstract:
    Echocardiograms and ECG were obtained for 11 hypothyroid dogs before and after levothyroxine supplementation (0.022 mg/kg of body weight, q 12 h for 64 +/- 12 days). Evidence of impaired left ventricular function was found in the dogs before treatment. A significant decrease in shortening fraction and velocity of circumferential fiber shortening, increase in left ventricular end-systolic diameter, and prolongation of preejection period was noted when comparing measurements before and after levothyroxine supplementation. Amplitude of the P and R waves was significantly higher after treatment than before. It was concluded that changes in cardiac function can be reversed in hypothyroid dogs.
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