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  • Title: Constitutive and inducible kappa B binding activities in the cytosol of v-Rel-transformed lymphoid cells.
    Author: Hodgson J, Enrietto PJ.
    Journal: J Virol; 1995 Mar; 69(3):1971-9. PubMed ID: 7853544.
    Abstract:
    Constitutive and inducible kapp B binding activities associated with v-Rel and c-Rel in the cytosol of v-Rel-transformed cells have been identified. These activities were resolved by electrophoretic mobility shift assay and chromatographic techniques into a high-molecular-weight protein-DNA complex designated complex I containing v- and c-Rel and lower-molecular-weight complexes II, III and IV which contained only v-Rel and which were stimulated by nucleotides, low pH, and detergent. These experiments suggest that interaction of v-Rel and c-Rel decreases the DNA-binding activity of each.
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