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Title: Aromatase activity in an estrogen-producing adrenocortical carcinoma in a young man. Author: Kimura M, Itoh N, Tsukamoto T, Kumamoto Y, Takagi Y, Mori Y. Journal: J Urol; 1995 Mar; 153(3 Pt 2):1039-40. PubMed ID: 7853554. Abstract: We report on a 19-year-old man with adrenocortical adenoma producing an excessive amount of estrogen. Determination of aromatase activity of the carcinoma tissue revealed its marked enhancement compared with that of 3 normal adrenal glands and the adipose tissue. The enhanced activity of aromatase was mainly responsible for the overproduction of estrogen in the adrenocortical carcinoma of our case.[Abstract] [Full Text] [Related] [New Search]