These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Multicenter double-blind study examining the antidepressant effectiveness of the hypericum extract LI 160.
    Author: Hänsgen KD, Vesper J, Ploch M.
    Journal: J Geriatr Psychiatry Neurol; 1994 Oct; 7 Suppl 1():S15-8. PubMed ID: 7857501.
    Abstract:
    Seventy-two depressive patients of 11 physicians' practices were treated in a double-blind study for a period of 6 weeks either with hypericum extract LI 160 or with placebo. Inclusion criterion was a major depression in accordance with DSM-III-R. The changes were assessed using four psychometric scales (HAMD, D-S, BEB, CGI). After 4 weeks of therapy, the statistical evaluation revealed a significant improvement in all four psychometric tests in the active group as compared to the placebo group. After switching the placebo group to active treatment (5th to 6th week of therapy), significant improvements were found in the original placebo group. No serious side effects were observed.
    [Abstract] [Full Text] [Related] [New Search]