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  • Title: [The effect of the isolated or group housing of rat pups weaned at different times from the lactating female on the development of a spectrum of digestive enzymes in the small intestine].
    Author: Vataeva LA, Egorova VV, Kassil' VG, Nikitina AA, Timofeeva NM.
    Journal: Zh Evol Biokhim Fiziol; 1994; 30(4):532-40. PubMed ID: 7863745.
    Abstract:
    Studies have been made on the formation of the spectrum of digestive enzymes in the small intestine of weanling rats which were taken from lactating female and given semisynthetic food at the age of 17, 21 and 25 days. It was shown that the rate of general development and maturation of the digestive enzymes depends on the age of animals and the mode of their breeding (isolated or in a group of the same age). These factors significantly affect also the level of the activity and proximo-distal gradient of distribution of the following intestinal enzymes: lactase, sucrase, alkaline phosphatase, alanine aminopeptidase, glycyl-L-leucine dipeptidase, as well as the mass of the mucose and protein content of the small intestine.
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