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  • Title: Phospholipids metabolism in platelets stimulated with collagen.
    Author: Ferri A, Calza R.
    Journal: Biochem Mol Biol Int; 1994 Oct; 34(4):693-8. PubMed ID: 7866294.
    Abstract:
    Collagen addition to platelets suspended in Calcium-free medium induces slow shape change followed by fast aggregates formation. Time courses of membrane phospholipids metabolism and arachidonic acid oxidative metabolism indicate that phospholipase C is the immediate target of the stimulus, and subsequently phospholipase A-2 is activated by synergistic action of released calcium and protein kinase C.
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