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  • Title: The effect of sodium 5,6-dimethyl-2-nitroindanedione on anaphylactic reactions in vitro.
    Author: Sharpe TJ, Ross JW, Spicer BA.
    Journal: Agents Actions; 1978 Apr; 8(3):199-202. PubMed ID: 78665.
    Abstract:
    A nitroindanedione (BRL 10833) inhibited the antigen induced release of histamine and slow reacting substance of anaphylaxis (SRS-A) from passively sensitized human lung at similar concentrations to those required for the inhibition of histamine release by disodium cromoglycate (DSCG). BRL 10833 was more potent than DSCG as an inhibitor of histamine release by antigen from actively and passively sensitized rat peritoneal cells and rat skin fragments.
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