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  • Title: Prolactin in systemic lupus erythematosus.
    Author: Pauzner R, Urowitz MB, Gladman DD, Gough JM.
    Journal: J Rheumatol; 1994 Nov; 21(11):2064-7. PubMed ID: 7869311.
    Abstract:
    OBJECTIVE: To estimate the prevalence and evaluate the clinical significance of hyperprolactinemia in a cohort of 82 consecutively reviewed patients with systemic lupus erythematosus (SLE). METHODS: Basal prolactin levels and clinical data were analyzed in 82 consecutive patients with SLE, and longitudinal studies were carried out in 30/82 patients. RESULTS: Hyperprolactinemia was not associated with active disease in the group as a whole (p = 0.145) or in longitudinal studies in 30 patients (p = 0.294). However, SLE was more often active in patients with hyperprolactinemia without any obvious causes (8/9 samples) compared with patients with known secondary causes for hyperprolactinemia (p = 0.088). CONCLUSION: Hyperprolactinemia is likely not associated with disease activity in SLE.
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