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  • Title: Long-term remission of neutropenia in Felty's syndrome after a short GM-CSF treatment.
    Author: Pereira J, Velloso ED, Loterio HA, Laurindo IM, Chamone DA.
    Journal: Acta Haematol; 1994; 92(3):154-6. PubMed ID: 7871957.
    Abstract:
    We report a case of Felty's syndrome in which neutropenia was corrected by a short-term treatment with recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF, 5 micrograms/kg/day s.c. for 14 days). Absolute neutrophil counts rose from 0.1 to 2.2 x 10(9)/l and remained > 1.0 x 10(9)/l 8 weeks after discontinuation of the GM-CSF therapy. A flare-up of arthritis and a decrease in platelet counts were observed.
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