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  • Title: [Liver involvement in Q fever and Mediterranean boutonneuse fever. Comparative study].
    Author: Abril López de Medrano V, Ortega González E, Ruiz Cavanilles C, Soler Ros JJ, Fraile Fariñas T, Monzo Inglés V, Herrera Ballester A.
    Journal: Rev Esp Enferm Dig; 1994 Dec; 86(6):891-3. PubMed ID: 7873263.
    Abstract:
    Rickettsia spp. infections produce hepatic damage with transaminases elevation and biological signs of cholostasis. Classical biochemical tests of hepatic function were analyzed and compared in 8 patients with Q Fever (QF) and 7 with Boutonneuse Mediterranean Fever (BMF). Liver enlargement was detected in 75% of the QF group of patients as compared with the 57% of the BMF group. Transaminases were raised in 75% of the patients of the QF group and in 85, 7% of the BMF patients. Only one patient in the QF group showed manifest clinical jaundice. Statistically significant differences were found between the values of AST, ALT, alkaline phosphatase and GGT, which were higher in the QF group. Liver involvement is more important in patients with QF than in FBM. There is a large percentage of clinically silent involvement in both diseases. Liver function tests should be carried out in infections by Rickettsia spp.
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