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  • Title: [Observation on prevention of hepatitis B virus transmission from mother to baby by hepatitis B vaccine].
    Author: Hu Z, Teng H, Han M.
    Journal: Zhonghua Liu Xing Bing Xue Za Zhi; 1994 Dec; 15(6):346-8. PubMed ID: 7874703.
    Abstract:
    Forty-two new-born infants whose mothers had been given HBV vaccine before marriage were undergone medical examination for six years. The results showed that the six-month seroconversion rates of anti-HBs among those infants, whose mothers had been immunized successfully, were 90.00% (9/10), and no one was infected by HBV. But the rates of those infants whose mothers were found to be HBsAg(+) and HBsAg/HBeAg(+) before or after marriage were 20.00% (2/10) and 18.18% (4/22), respectively, being much lower than the former. The rates of HBsAg(+) were 70.00% (7/10) and 68.18% (15/22), respectively. This led to the conclusion that immunization with HBV vaccine before marriage will partly break the HBV transmission chain of "couples-mother and her baby-population".
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