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  • Title: Apparent recurrence of progressive systemic sclerosis in a renal allograft.
    Author: Woodhall PB, McCoy RC, Gunnells JC, Seigler HF.
    Journal: JAMA; 1976 Aug 30; 236(9):1032-4. PubMed ID: 787567.
    Abstract:
    A young woman with progressive systemic sclerosis (PSS) and renal failure who received a renal transplant from her mother suffered accelerated loss of allograft function in the absence of hyperacute rejection or severe hypertension. A biopsy specimen and pathologic examination of the transplanted organ showed a fluorescent antibody pattern and vascular changes that were indistinguishable from those in the patient's native kidneys. This clinical sequence is a departure from the relative success of renal transplantation in the few previously reported cases of PSS where it has been used as therapy for renal failure.
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